#MonohybridInheritance

#Biology

#Inheritance

Inheritance: definitions

• Inheritance is the transmission of genetic information from one generation to the next generation

• A gene is a short length of DNA found on a chromosome that codes for a particular characteristic (expressed by the formation of different proteins)

• Alleles are variations of the same gene

  • As we have two copies of each chromosome, we have two copies of each gene and therefore two alleles for each gene

  • One of the alleles is inherited from the mother and the other from the father

  • This means that the alleles do not have to ‘say’ the same thing

  • For example, an individual has two copies of the gene for eye colour but one allele could code for brown eyes and one allele could code for blue eyes

• The observable characteristics of an organism (seen just by looking - like eye colour, or found – like blood type) is called the phenotype

• The combination of alleles that control each characteristic is called the genotype

• Alleles can be dominant or recessive

  • A dominant allele only needs to be inherited from one parent in order for the characteristic to show up in the phenotype

  • A recessive allele needs to be inherited from both parents in order for the characteristic to show up in the phenotype.

  • If there is only one recessive allele, it will remain hidden and the dominant characteristic will show

• If the two alleles of a gene are the same, we describe the individual as being homozygous (homo = same)

  • An individual could be homozygous dominant (having two copies of the dominant allele), or homozygous recessive (having two copies of the recessive allele)

• If the two alleles of a gene are different, we describe the individual as being heterozygous (hetero = different)

• When completing genetic diagrams, alleles are abbreviated to single letters

  • The dominant allele is given a capital letter and the recessive allele is given the same letter, but lower case

• We cannot always tell the genotype of an individual for a particular characteristic just by looking at the phenotype – a phenotype associated with a dominant allele will be seen in both a dominant homozygous and a dominant heterozygous genotype

• If two individuals who are both identically homozygous for a particular characteristic are bred together, they will produce offspring with exactly the same genotype and phenotype as the parents - we describe them as being ‘pure breeding’ as they will always produce offspring with the same characteristics

• A heterozygous individual can pass on different alleles for the same characteristic each time it is bred with any other individual and can therefore produce offspring with a different genotype and phenotype than the parents - as such, heterozygous individuals are not pure breeding

  
  

What is monohybrid inheritance?

• Monohybrid inheritance is the inheritance of characteristics controlled by a single gene (mono = one)

• This can be determined using a genetic diagram known as a Punnett square

• A Punnett square diagram shows the possible combinations of alleles that could be produced in the offspring

• From this the ratio of these combinations can be worked out

• Remember the dominant allele is shown using a capital letter and the recessive allele is shown using the same letter but lower case

Monohybrid Inheritance Example

• The height of pea plants is controlled by a single gene that has two alleles: tall and short

• The tall allele is dominant and is shown as T

• The small allele is recessive and is shown as t

• The term ‘pure breeding’ indicates that the individual is homozygous for that characteristic

What is a monohybrid cross?

• A monohybrid cross is the genetic mix between two individuals which determines a characteristic controlled by a single gene

• A genetic diagram is used to predict the possible outcome of a cross

How to construct Punnett squares

• Determine the parental genotypes

• Select a letter that has a clearly different lower case, for example: Aa, Bb, Dd

• Split the alleles for each parent and add them to the Punnett square around the outside

• Fill in the middle four squares of the Punnett square to work out the possible genetic combinations in the offspring

• You may be asked to comment on the ratio of different allele combinations in the offspring, calculate a percentage chances of offspring showing a specific characteristic or just determine the phenotypes of the offspring

• Completing a Punnett square allows you to predict the probability of different outcomes from monohybrid crosses

Identifying an unknown genotype

• Breeders can use a test cross to find out the genotype of an organism showing the dominant phenotype

• This involves crossing the unknown individual with an individual showing the recessive phenotype - if the individual is showing the recessive phenotype, then its genotype must be homozygous recessive

• By looking at the ratio of phenotypes in the offspring, we can tell whether the unknown individual is homozygous dominant or heterozygous

• The short plant is showing the recessive phenotype and so must be homozygous recessive - tt

Determining genotypes from offspring

• If the tall plant is homozygous dominant, all offspring produced will be tall

• If the tall plant is heterozygous, half the offspring will be tall and the other half will be short