Introduction
The red blood cells can't regenerate on their own because they don't have nucleus.
This allows the cell more room to store hemoglobin, the oxygen-binding protein, enabling the RBC to transport more oxygen.
Erythropoiesis is red blood cell (erythrocyte) production.
Your bone marrow makes most of your red blood cells.
Once they’re fully mature, they’re released into your bloodstream, where they transport oxygen throughout your body.
Problems with erythropoiesis can result in anemia, a condition that involves not having enough red blood cells.
Erythropoiesis is one type of hematopoiesis. Hematopoiesis is your body’s process of making all three types of blood cells: red blood cells (erythropoiesis), white blood cells (leukopoiesis) and platelets (thrombopoiesis).
Stages
Proerythroblast: The first stage, this cell is large and basophilic, with a large nucleus.
Erythroblast: An HSC matures into an erythroblast, which then becomes an immature RBC.
Reticulocyte: This immature RBC is slightly larger than a mature RBC and contains RNA in its cytoplasm.
Erythrocyte: The fully mature RBC, which is biconcave and transports oxygen and carbon dioxide
between
the lungs and tissues.
The Diagram :
The hormone erythropoietin (EPO).
Hemoglobin synthesis begins during the intermediate normoblast stage of erythropoiesis, the process of red blood cell (RBC) formation and development.
Seven Days.
Erythropoiesis starts in mesoderm of the yolk sac from third week to third month in the embryo.
Anemia is a common condition that occurs when the body doesn't have enough healthy red blood cells or hemoglobin to carry oxygen to the body's tissues.
Hemocytoblasts are stem cells found in bone marrow that can develop into any type of blood cell.
Vitamin B9, Vitamin B2,
Vitamin B12,
Vitamin C, Vitamin B,
Vitamin B6.
1.Which hormone triggers erythropoiesis?
2. At what stage of erythropoiesis does the synthesis of haemoglobin start?
3. RBC production takes about how many days?
4. In the foetus erythropoiesis starts in:
5. What is Anaemia?
6. What is hemocytoplasts?
7. Which vitamins are necessary for RBC production?