#Erythropoiesis

#Biology

#AnatomyofBones

Introduction

• The red blood cells can't regenerate on their own because they don't have nucleus.

• This allows the cell more room to store hemoglobin, the oxygen-binding protein, enabling the RBC to transport more oxygen.

• Erythropoiesis is red blood cell (erythrocyte) production.

• Your bone marrow makes most of your red blood cells.

  Once they’re fully mature, they’re released into your bloodstream, where they transport oxygen throughout your body.

• Problems with erythropoiesis can result in anemia, a condition that involves not having enough red blood cells.

• Erythropoiesis is one type of hematopoiesis. Hematopoiesis is your body’s process of making all three types of blood cells: red blood cells (erythropoiesis), white blood cells (leukopoiesis) and platelets (thrombopoiesis).

Stages

• Proerythroblast: The first stage, this cell is large and basophilic, with a large nucleus.

• Erythroblast: An HSC matures into an erythroblast, which then becomes an immature RBC.

• Reticulocyte: This immature RBC is slightly larger than a mature RBC and contains RNA in its cytoplasm.

    

•  Erythrocyte: The fully mature RBC, which is biconcave and transports oxygen and carbon dioxide

  between

  the lungs and tissues.

• The Diagram :

The Video